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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepulveda, Xiang Li, Xiaojing Yue, et al.



Selected by Mansi

Aurora B controls microtubule stability to regulate abscission dynamics in stem cells

Snježana Kodba, Amber Öztop, Eri van Berkum, et al.



Selected by Ines Jmel-Boyer

Scalable and efficient generation of mouse primordial germ cell-like cells

Xinbao Ding, Liangdao Li, Jingyi Gao, et al.



Selected by Carly Guiltinan

FoxO transcription factors actuate the formative pluripotency specific gene expression programme

Laura Santini, Saskia Kowald, Giovanni Sestini, et al.



Selected by Mansi

Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and airway dysfunction

Diego A. López, Aleah Griffin, Lorena Moreno Aguilar, et al.



Selected by Marina Schernthanner

Interspecies blastocyst complementation generates functional rat cell-derived forebrain tissues in mice

Jia Huang, Bingbing He, Xiali Yang, et al.



Selected by Martin Estermann

Alumni

Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise

Amir D. Hay, Noah J. Kessler, Daniel Gebert, et al.



Selected by Samantha Seah et al.

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.



Selected by Diego Martínez

A specialized mRNA translation circuit instated in pluripotency presets the competence for cardiogenesis in humans

Deniz Bartsch, Kaustubh Kalamkar, Gaurav Ahuja, et al.



Selected by Emma Armitage

stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult stem and Progenitor cells

Yun-Kyo Kim, Miguel Ramalho-Santos



Selected by Vanessa Luzak

Microstructured hydrogels to guide self-assembly and function of lung alveolospheres

Claudia Loebel, Aaron I. Weiner, Jeremy B. Katzen, et al.



Selected by Julio Sainz de Aja

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